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  "notes": "New and recent evidence (see references 1-12) shows that 
            
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cotrimoxazole (CTX) preventive therapy is associated with a 25-46% 
            
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reduction in mortality in sub-Saharan Africa, even in areas with high 
            
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bacterial resistance to the antibiotic. CTX preventive therapy also 
            
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decreases the frequency of clinic visits and hospitalisations, 
            
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improves weight and reverses the decline in CD4-lymphocyte counts and 
            
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the rise in HIV viral loads. Efficacy seems to be maintained over the 
            
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1-2 year follow-up periods of the studies. CTX preventive therapy in 
            
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Africa has few adverse reactions and there are high levels of 
            
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adherence. In summary, CTX is a safe, cheap and readily available 
            
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anti-microbial agent, which can extend and improve the quality of 
            
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in 2001, initially as a unit in the Department of Clinical Services, 
            
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to coordinate the biomedical HIV Program in Malawi. The department now 
            
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circumcision program (VMMC). All these HIV program sub-sections are 
            
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linked to one robust monitoring and evaluation sub-section in the HIV 
            
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and AIDS Department which technically operates under the Central 
            
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Monitoring and Evaluation Department (CMED) of the Ministry of 
            
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Health.",
            
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